Evidence for melanin concentrating hormone (MCH) receptors mediating melanosome aggregation in Labeo melanophores.
نویسندگان
چکیده
Melanin concentrating hormone (MCH: 5 x 10(-12)-5 x 10(-8) M) induced a concentration related, rapid and reversible pigment aggregation in innervated melanophores of Labeo rohita. In inducing melanosome aggregation MCH was found to be 10(4) times more potent than norepinephrine. Experiments employing phentolamine and propranolol suggest that MCH acts through its own specific receptors on the melanophores unrelated to adrenoceptors. MCH was able to aggregate the melanosomes even in the absence of extracellular Ca2+.
منابع مشابه
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ورودعنوان ژورنال:
- Indian journal of physiology and pharmacology
دوره 34 3 شماره
صفحات -
تاریخ انتشار 1990